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Michael Freeman, PhD

Director, Division of Cancer Biology and Therapeutics Research in the Department of Biomedical Sciences

Director, Basic Science Research in the Department of Surgery

Professor, Biomedical Sciences

Professor, Surgery

Vice Chair, Surgical Research in the Department of Surgery

Michael Freeman, PhD

Director, Division of Cancer Biology and Therapeutics Research in the Department of Biomedical Sciences

Director, Basic Science Research in the Department of Surgery

Professor, Biomedical Sciences

Professor, Surgery

Vice Chair, Surgical Research in the Department of Surgery

The research of Michael Freeman, PhD, focuses on urogenital tract physiology, with a primary focus on cancer progression to lethal disease. Prostate cancer is an area of strong emphasis. Freeman also has interest and substantial publication history in molecular studies of bladder cancer, breast cancer, smooth muscle regulation and dysfunction, and interstitial cystitis/pelvic pain syndrome.

  • Associate Editor: American Journal of Pathology, Current
  • John K. Lattimer Award, 2010
  • Distinguished Mentor Award, American Urological Association Foundation, 2004
  • President, Society for Basic Urologic Research, 2002-03
  • MERIT Award, National Institutes of Health, 2001
  • Di Vizio D, Morello M, Dudley AC, Schow PW, Adam RM, Morley S, Mulholland D, Rotinen M, Hager MH, Insabato L, Moses MA, Demichelis F, Lisanti MP, Wu H, Klagsbrun M, Bhowmick NA, Rubin MA, D'Souza-Schorey C, Freeman MR. Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. Am J Pathol. 2012 Nov;181(5):1573-1584.
  • Hager MH, Morley S, Bielenberg DR, Gao S, Morello M, Holcomb IN, Liu W, Mouneimne G, Demichelis F, Kim J, Solomon KR, Adam RM, Isaacs WB, Higgs HN, Vessella RL, Di Vizio D, Freeman MR. DIAPH3 governs the cellular transition to the amoeboid tumour phenotype. EMBO Mol Med. 2012 Aug;4(8):743-760
  • Kim J, Di Vizio D, Kim TK, Kim J, Kim M, Pelton K, Clinton SK, Hai T, Hwang D, Solomon KR, Freeman MR. The response of the prostate to circulating cholesterol: activating transcription factor 3 (ATF3) as a prominent node in a cholesterol-sensing network. PLoS One. 2012;7(7):e39448.
  • Kim J, Kim WJ, Liu Z, Loda M, Freeman MR. The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer. Cell Cycle. 2012 Mar 15;11(6):1123-1130.
  • Liu Z, Zanata SM, Kim J, Peterson MA, Di Vizio D, Chirieac LR, Pyne S, Agostini M, Freeman MR, Loda M. The ubiquitin-specific protease USP2a prevents endocytosis-mediated EGFR degradation. Oncogene. 2013 Mar 28;32(13):1660-1669.

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Many of the physicians who have medical staff privileges to practice medicine at Cedars-Sinai Medical Center are independent physicians, and not employees or agents of the hospital. These independent physicians bill separately for their services. You should contact your physician to determine their status and billing practices.

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