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Cathryn Kolka, PhD

Assistant Professor, Biomedical Sciences

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Cathryn Kolka, PhD

Assistant Professor, Biomedical Sciences

The research of Cathryn Kolka, PhD, focuses on the role of the vascular system in the metabolic effects of insulin. While earning her PhD in biochemistry at the University of Tasmania, she investigated the role of blood flow distribution on metabolism. Kolka's current studies investigate the ability of insulin to access skeletal muscle in diet induced obesity, insulin resistance and diabetes, and emphasize the physiological role of the vascular endothelium on metabolic outcomes. Her projects measure access of insulin to muscle, a major component of insulin sensitivity, and how this is altered by diabetes and insulin resistance. She tests molecules that increase access to improve insulin sensitivity in animals models and is developing imaging models to visualize insulin movement in vivo.

View NIH Biographical Sketch as a PDF

  • Doctorate: University of Tasmania, 2006
  • Post Doctorate: Keck School of Medicine of USC, 2010
  • Reviewer: American Journal of Physiology and Diabetologia, Current
  • American Heart Association, 2012
  • Faculty of 1000 Recommendation, 2012
  • Obesity Society, 2011
  • Pat Simons Award, Obesity Society. Recognizing Research Excellence by Young Investigators, 2009

Click here for a list of peer-reviewed publications.

  • Kolka CM, Richey JM, Castro AV, Broussard JL, Ionut V, Bergman RN. Lipid-induced insulin resistance does not impair insulin access to skeletal muscle. Am J Physiol Endocrinol Metab. 2015;308(11):E1001-1009.
  • Kolka CM, Castro AV, Kirkman, EL, Bergman RN. Modest Hyperglycemia prevents interstitial dispersion of insulin in skeletal muscle. Metabolism. 2015;64(2):330-337.
  • Kolka CM, Bergman RN. The barrier within: endothelial transport of hormones. Physiology (Bethesda). 2012;27(4):237-247.
  • Chiu JD, Kolka CM, Richey JM, Harrison LN, Zuniga E, Kirkman EL, Bergman RN. Experimental hyperlipidemia dramatically reduces access of insulin to canine skeletal muscle. Obesity (Silver Spring). 2009;17(8):1486-1492.
  • Kolka CM, Harrison LN, Lottati M, Chiu JD, Kirkman EL, Bergman RN. Diet-induced obesity prevents interstitial dispersion of insulin in skeletal muscle. Diabetes. 2009;59(3):619-626.
  • Kolka CM, Rattigan S, Richards S, Clark MG. Metabolic and vascular actions of endothelin-1 are inhibited by insulin-mediated vasodilation in perfused rat hindlimb muscle. Br J Pharmacol. 2005;145(7):992-1000.

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