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Gislaine Martins, PhD

Assistant Professor, Medicine

Director, Flow Cytometry Core in the Inflammatory Bowel and Immunobiology Research Institute

Research Scientist, Inflammatory Bowel & Immunobiology Research Institute

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310-423-0278

Gislaine Martins, PhD

Assistant Professor, Medicine

Director, Flow Cytometry Core in the Inflammatory Bowel and Immunobiology Research Institute

Research Scientist, Inflammatory Bowel & Immunobiology Research Institute

The laboratory of Gislaine Martins, PhD studies molecular regulation of immune responses, and focuses on transcriptional regulation of T lymphocyte terminal effector differentiation and its implication in inflammatory diseases.

  • Master's: University of Sao Paulo, 1998
  • Doctorate: University of Sao Paulo, School of Medicine of Ribeirao Preto, 2002
  • Post Doctorate: University of Pennsylvania School of Medicine, 2004
  • Post Doctorate: Columbia University College of Physicians and Surgeons-NYC, 2008
  • Keystone Symposia Early Career Investigator Travel Award, 2014
  • New Faculty Travel Award-AAI, 2013
  • Society for Mucosal Immunology, 2009
  • Invitrogen Trainee Achievement Award American Association of Immunologists, 2008
  • American Association of Immunologists, 2006
  • Welcome Trust Scholarship, 2000
  • Young Investigator Award Brazilian Society of Biochemistry and Molecular Biology, 2000
  • Regional Council of Biologists (Brazil), 1998
  • Brazilian Society of Protozoology, 1997
  • Brazilian Society of Immunology, 1996

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  • Benevides L, da Fonseca DM, Donate PB, Tiezzi DG, De Carvalho DD, de Andrade JM, Martins GA, Silva JS. IL17 promotes mammary tumor progression by changing the behavior of tumor cells and eliciting tumorigenic neutrophils recruitment. Cancer Res. 2015;75(18):3788-3799.
  • Salehi S, Benevides L, Willen J, Keech N, Dhall D, Meffre E, Targan S, Martins G. B lymphocyte–induced maturation protein-1 contributes to intestinal mucosa homeostasis by limiting the number of IL-17–producing CD4+ T Cells. J Immunol. 2012;189(12):5682-5693.
  • Rutishauser RL, Martins GA, Kalachikov S, Chandele A, Parish IA, Meffre E, Jacob J, Calame K, Kaech SM. Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. Immunity. 2009;31(2):296-308.
  • Martins GA, Calame KL. Regulation and functions of Blimp-1 in T and B lymphocytes. Annu Rev Immunol. 2008;26:133-169.
  • Martins GA, Cimmino L, Liao J, Magnusdottir E, Calame K. Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival. J Exp Med. 2008;205(9):1959-1965.
  • Cimmino L, Martins GA, Liao J, Magnusdottir E, Grunig G, Perez RK, Calame KL. Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression. J Immunol. 2008;181(4):2338-2347.

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