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Barry Stripp, PhD

Bram and Elaine Goldsmith Chair in Gene Therapeutics Research

Director, Pulmonary Stem Cell Research

Professor, Medicine

Professor, Biomedical Sciences

Barry Stripp, PhD

Bram and Elaine Goldsmith Chair in Gene Therapeutics Research

Director, Pulmonary Stem Cell Research

Professor, Medicine

Professor, Biomedical Sciences

The research of Barry Stripp, PhD, focuses on lung stem/progenitor cell biology and defining mechanisms of normal tissue maintenance, repair and remodeling in disease. The Stripp Laboratory is particularly interested in understanding epithelial defects that contribute to the development of fibrotic lung disease and identifying new therapeutic approaches to help patients afflicted with these lung disorders.

  • Chen H, Matsumoto K, Brockway BL, Rackley CR, Liang J, Lee JH, Jiang D, Noble PW, Randell SH, Kim CF, Stripp BR. Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury. Stem Cells. 2012 Sep;30(9):1948-1960.
  • Giangreco A, Arwert EN, Rosewell IR, Snyder J, Watt FM, Stripp BR. Stem cells are dispensable for lung homeostasis but restore airways after injury. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9286-9291.
  • Hashimoto S, Chen H, Que J, Brockway BL, Drake JA, Snyder JC, Randell SH, Stripp BR. β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium. J Cell Sci. 2012 Feb 15;125(Pt 4):932-942.
  • Lee JH, Bhang DH, Beede A, Huang TL, Stripp BR, Bloch KD, Wagers AJ, Tseng YH, Ryeom S, Kim CF. Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis. Cell. 2014 Jan 30;156(3):440-455.
  • Rackley CR, Stripp BR. Building and maintaining the epithelium of the lung. J Clin Invest. 2012 Aug;122(8):2724-2730.
  • Snyder JC, Reynolds SD, Hollingsworth JW, Li Z, Kaminski N, Stripp BR. Clara cells attenuate the inflammatory response through regulation of macrophage behavior. Am J Respir Cell Mol Biol. 2010 Feb;42(2):161-171.

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