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Shawn Wagner, PhD

Technical Director, Small Animal MRI in the Biomedical Imaging Research Institute

Assistant Professor, Biomedical Sciences

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310-423-7519

Shawn Wagner, PhD

Technical Director, Small Animal MRI in the Biomedical Imaging Research Institute

Assistant Professor, Biomedical Sciences

The research of Shawn Wagner, PhD, focuses on hyperpolarization, a new and emerging field within magnetic resonance imaging, which provides enhancement of signal over 10,000 times what is currently available. His current research utilizes a method of polarization using parahydrogen to transfer the polarization from the hydrogen nuclei to a carbon or nitrogen nucleus with a slower signal decay allowing for in vivo studies, focusing on prostate and breast cancer.

  • Doctorate: University of Virginia, 1999
  • Member, American Association of Cancer Research, 2011
  • Safety Committee, International Society for Magnetic Resonance in Medicine, 2011-2013
  • Member, International Society for Magnetic Resonance in Medicine, 2007-current
  • President of ISMRM Methods and Equipment Study Group, 2016

Click here for a list of peer-reviewed publications.

  • McCormick J, Grunfeld AM, Ertas YN, Biswas AN, Marsh KL, Wagner S, Glöggler S, Bouchard L-S. Aqueous Ligand-Stabilized Palladium Nanoparticle Catalysts for Parahydrogen-Induced 13C Hyperpolarization. Anal Chem. 2017 Jul 5;89(13):7190-7194. Epub 2017 Jun 20.
  • Zacharias N, McCullough CR, Wagner S, Sailasuta N, Chan HR, Lee Y, Hu J, Perman WH, Henneberg C, Ross BD, et al. Towards Real-time Metabolic Profiling of Cancer with Hyperpolarized Succinate. J Mol Imaging Dyn. 2016 Jun;6(1). Epub 2016 Jan 11.
  • Gloggler S, Grunfeld AM, Ertas YN, McCormick J, Wagner S, Bouchard LS. Surface ligand-directed pair-wise hydrogenation for heterogeneous phase hyperpolarization. Chem Commun (Camb). 2016 Jan 11;52(3):605-608. Epub 2015 Nov 10.
  • Patil R, Ljubimov AV, Gangalum PR, Ding H, Portilla-Arias J, Wagner S, Inoue S, Konda B, Rekechenetskiy A, Chesnokova A, et al. MRI virtual biopsy and treatment of brain metastatic tumors with targeted nanobioconjugates: nanoclinic in the brain. ACS Nano. 2015 May 26;9(5):5594-608. Epub 2015 May 6.
  • Gloggler S, Wagner S, Bouchard LS. Hyperpolarization of amino acid derivatives in water for biological applications. Chem Sci. 2015;6(7):4261-4266.

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