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Ali Khoynezhad, MD, FACS

Director, Thoracic Aortic Surgery Program

Advanced Health Sciences Pavilion
127 S. San Vicente Blvd
Suite A3606
Los Angeles, CA 90048





Ali Khoynezhad, MD, FACS

Director, Thoracic Aortic Surgery Program

  • Surgery-Cardio-Thoracic

Abdominal Aortic Aneurysms

Aortic Aneurysms

Aortic Dissections

Aortic Regurgitation

Aortic Stenosis

Aortic Valve Surgery / Surgeries

Aortic Valve-Sparing Surgery / Surgeries

Arrhythmias (Irregular Heartbeat, Heart Rhythm Disorders)

Atrial Fibrillation

Connective Tissue Diseases

Coronary Artery Bypass Surgery / Surgeries (CABG)


Heart Valve Surgery / Surgeries

Marfan's Syndrome


Pulmonary Embolisms

Radiofrequency Ablation

Thoracic Aortic Aneurysms

Tricuspid Valve Surgery


Research Focus:Spinal cord ischemia resulting in paraplegia may be attenuated using novel anti-inflammatory medication such as NMDA-receptor blockers, adjuncts such as ischemic pre- and post-conditioning, and novel stem cell therapeutics. The effectiveness of these promising agents are tested validated in animal model, effective dose-response is established, prior to first-in-human experiments. Second project entails transcatheter aortic valve replacement in mechanical aortic valve prosthesis.Research Contributions:Leader in outcome research of patients undegoing open and endovascular procedures for aortic dissection; developed classification for endovascular repair of acute type B dissection predicting false lumen-patency in mid- and long-term follow-up.Current investigations:Modulating ischemic response of spinal cord. Developing in vitro model of acute type A dissection. Endovascular repair of aortic root and ascending aorta. Transcatheter valve replacement in patients with mechanical aortic valve. Microsurgical approach to intracardiac operation using transfemoral access. Minimal-invasive endoluminal cardotid-subclavian bypass. Transcatheter aortic valve replacement in mechanical aortic valve prosthesis.

View NIH Biographical Sketch as a PDF

  • Medical School: University of Cologne, College of Medicine, Germany, 1996
  • Internship: Wake Forest University Baptist Medical Center, NC, 1999
  • Residency: North Shore University - LIJ Medical Center, NY, 2003
  • Fellowship: Harbor-UCLA Medical Center, CA, 2005
  • Fellowship: Montefiore Medical Center, NY, 2005

View CV as a PDF

  • American College of Surgeons, Murray Friedman Award, 2002
  • American College of Chest Physicians: Poster of Distinction Award., 2002
  • Research Innovation Award: University of Nebraska Medical Center., 2008
  • American College of Surgeons: German Traveling Fellowship Award., 2011
  • Section Editor: Operative Techniques in Thoracic and Cardiovascular Surgery, 2013
  • Editor, The Cardiothoracic Surgery Network, Endovascular Portal., 2006 - 2013
  • 21st Century Cardiothoracic Surgical Society, 2014
  • Thoracic Surgery Foundation Research & Education Leadership Scholarship at Brandeis University., 2014
  • Society for University Surgeons, 2014
  • American Association for Thoracic SurgeryMember: Annual Meeting Video CommitteeMember: Publication CommitteeMember: Scientific Affairs & Government RelationsChair: Web Editorial BoardChair: Technology Committee, 2010 - 2015

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Click here for a list of peer-reviewed publications.

  • Khoynezhad A, et al. Apoptosis: pathophysiology and therapeutic implications for the cardiovascular surgeon. Ann Thorac Surg 2004;78(3):1109-1118.
  • Khoynezhad A, et al. Improved outcome after repair of descending and thoracoabdominal aortic aneurysms using modern adjuncts. Interact CardioVasc Thorac Surg 2005;4:574-6.
  • Khoynezhad A, et al. Techniques and Results of Endovascular Management of Acute Complicated Type B Aortic Dissection in North America. Rev Cardiovasc Med 2012;13(4):e176-84.
  • Brecht R, Friedrich M, Heinisch PP, Plonien K, Akra B, Hagl C, Khoynezhad A, et al. Transcatheter Valve Replacement: New Concepts for Microsurgery Inside the Heart, Innovation 2013;8(1):29-36.
  • Swerdlow CD, Kass RM, Khoynezhad A. Inside-Out Insulation Failure of a Defibrillator Lead with Abrasion-Resistant Coating. Heart Rhythm 2013; 10(6):e73.
  • Khoynezhad A, et al. One-Year Results of the RESCUE Trial: TEVAR for Traumatic Aortic Injury Remains a Favorable Therapeutic Approach at Midterm Follow-up. J Thorac Cardiovasc Surg 2015;149(1):155-61.

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