Adam N. Mamelak, MD

Co-Director, Pituitary Center

Director, Functional Neurosurgery Program

Professor, Neurosurgery

Advanced Health Sciences Pavilion, A6600
127 S. San Vicente Blvd.
Los Angeles, CA 90048





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Adam N. Mamelak, MD

Co-Director, Pituitary Center

Director, Functional Neurosurgery Program

Professor, Neurosurgery

  • Neurosurgery
  • Pituitary


Brain Cancers (Glioma)

Brain Tumors

Cushing's Disease

Deep Brain Stimulation


Epilepsy Surgery / Surgeries

Essential Tremors


Parkinson's Disease

Pineal Gland Disorders

Pituitary Disorders

Pituitary Tumors

Skull Base Tumors

Stereotactic Radiosurgery

Vagus Nerve Stimulation (VNS Therapy)

The research focus of Adam N. Mamelak, MD, is pituitary tumor and endoscopic skull base surgery technical development. He is developing and testing new equipment and methods for minimally invasive surgery of pituitary and skull base tumors, and studying the pathogenesis of these tumors. He is also interested in neural basis of learning and memory through studying the neuro-physiological basis of memory processes in patients with implanted electrodes for identification of seizures or undergoing deep brain stimulation. Mamelak is looking into fluorescent guided removal of brain tumors.

View NIH Biographical Sketch as a PDF

  • Medical School: Harvard School of Medicine, 1990
  • Fellowship: University of California, San Francisco Medical Center, 1995
  • Residency: University of California, San Francisco Medical Center, 1996
  • Post Doctorate: California Institute of Technology, 1997

View CV as a PDF

  • Best Doctors, 2011-present
  • Member, International Society of Pituitary Surgeons, 2007-present
  • Member, Pituitary Society, 2007-present
  • Ad Hoc Reviewer: Epilepsia, 2003-present
  • Fellow, American College of Surgeons, 2001-Present
  • Member, Society of Neuro-Oncology, 1998-present
  • National Brain Tumor Foundation AANS/CNS Award for Best Translational Research, 1999
  • Young Clinician Investigator Award, American Association Neurological Surgeons, 1997
  • Junior Investigator Award, American Epilepsy Society, 1997
  • Benjamin G. Brown Scholarship for Scientific Excellence, 1985

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Click here for a list of peer-reviewed publications.

  • Mamelak AN, Dowd CF, Tyrrell JB, McDonald JF, Wilson CB. Venous angiography is needed to interpret inferior petrosal sinus and cavernous sinus sampling data for lateralizing adrenocorticotropin-secreting adenomas. J Clin Endocrinol Metab. 1996;81(2):475-481.
  • Mamelak AN, Lopez N, Akhtari M, Sutherling WW. Magnetoencephalography-directed surgery in patients with neocortical epilepsy. J Neurosurg. 2002;97(4):865-873.
  • Mamelak AN, Rosenfeld S, Bucholz R, Raubitschek A, Nabors LB, Fiveash JB, Shen S, Khazaeli MB, Colcher D, Liu A, et al. Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade glioma. J Clin Oncol. 2006;24(22):3644-3650.
  • Quattrochi JJ, Mamelak AN, Madison RD, Macklis JD, Hobson JA. Mapping neuronal inputs to REM sleep induction sites with carbachol-fluorescent microspheres. Science. 1989;245(4921):984-986.
  • Rutishauser U, Mamelak AN, Schuman EM. Single-trial learning of novel stimuli by individual neurons of the human hippocampus-amygdala complex. Neuron. 2006;49(6):805-813.
  • Rutishauser U, Schuman EM, Mamelak AN. Activity of human hippocampal and amygdala neurons during retrieval of declarative memories. Proc Natl Acad Sci USA. 2007;105(1):329-334.

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Adam N. Mamelak, MD, FACS, FAANS

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