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John S. Yu, MD

Director, Surgical Neuro-Oncology

Professor, Neurosurgery

Surgical Director, Neuro-Oncology

Vice Chair, Neurosurgical Oncology in the Department of Neurosurgery

127 S. San Vicente Blvd.
Advanced Health Sciences Pavilion, A6600
Los Angeles, CA 90048

Phone:

310-423-7900

Fax:

310-423-0777

Parking Instructions:

Parking is available in Lot 4 on Sherbourne Drive.

John S. Yu, MD

Director, Surgical Neuro-Oncology

Professor, Neurosurgery

Surgical Director, Neuro-Oncology

Vice Chair, Neurosurgical Oncology in the Department of Neurosurgery

  • Neurosurgery

Acoustic Neuromas

Astrocytoma

Brain Cancer Vaccine

Brain Cancers (Glioma)

Brain Cysts

Brain Lesions

Brain Tumors

Ependymomas

Frontal Lobe Tumors

Glioblastoma Multiforme

Immunotherapy

Meningiomas

Neuromas

Oligodendrogliomas

Spine Tumors (Cervical, Thoracic, Lumbar, Sacral)

Stereotactic Radiosurgery

Trigeminal Neuralgia

The research of John S. Yu, MD, focuses on immune and stem cell therapy for brain tumors, cancer stem cells and their microenvironment in brain tumors. Yu also researches cancer stem cell-specific cytotoxic T lymphocytes, cancer stem cell signaling, mechanism of cancer invasion, cancer stem cell-specific cytotoxic T lymphocytes, targeted immunochemotherapy using nanotechnology, and development of imaging and diagnostic agents using nanoparticles.

  • Undergraduate: Stanford University, 1985
  • Fellowship: National Institute of Mental Health, 1989
  • Medical School: Harvard Medical School, 1990
  • Master's: Harvard-MIT Division of Health Sciences and Technology, 1990
  • Residency: Massachusetts General Hospital, 1997
  • America's Top Cancer Specialists, Newsweek, 2007-present
  • Southern California Super Doctors, Los Angeles Magazine, 2007-present
  • America'a Top Doctors, Castle and Connolly, 2005-present
  • Culpeper Scholar, Molecular Neurogenenics, Massachusetts General Hospital
  • Preuss Award, Joint Section on Tumors, American Association of Neurological Surgeons and Congress of Neurological Surgeons
  • Academy Award, American Academy of Neurological Surgery
  • Mahaley Clinical Research Award, American Association of Neurological Surgeons and Congress of Neurological Surgeons

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Click here for a list of peer-reviewed publications.

  • Phuphanich S, Wheeler CJ, Rudnick JD, Mazer M, Wang HQ, Nuno MA, Richardson JE, Fan X, Ji J, Chu RM, Bender JM, Hawkins ES, Patil CG, Black KL, Yu JS. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma. Cancer Immunol Immunother. 2013;62(1):125-135.
  • Lee BS, Amano T, Wang HQ, Pantoja JL, Yoon CW, Hanson CJ, Amatya R, Yen A, Black KL, Yu JS. Reactive oxygen species responsive nanoprodrug to treat intracranial glioblastoma. ACS Nano. 2013;7(4):3061-3077.
  • Ji J, Judkowski VA, Liu G, Wang H, Bunying A, Li Z, Xu M, Bender J, Pinilla C, Yu JS. Identification of novel HLA-A*0201-restricted, cytotoxic T lymphocyte epitopes on CD133 for cancer stem cell immunotherapy. Stem Cells Transl Med. 2014;3(3):356-364.
  • Xu Q, Liu G, Yuan X, Xu M, Wang H, Ji J, Konda B, Black KL, Yu JS. Antigen-specific T cell response from dendritic cell vaccination using cancer stem-like cell-associated antigens. Stem Cells. 2009;27(8):1734-1740.

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