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Leon G. Fine, MD

Chair, Department of Biomedical Sciences

Director, Graduate Research Education

Professor, Medicine

Professor, Biomedical Sciences

Vice Dean, Research and Graduate Research Education

Leon G. Fine, MD

Chair, Department of Biomedical Sciences

Director, Graduate Research Education

Professor, Medicine

Professor, Biomedical Sciences

Vice Dean, Research and Graduate Research Education

  • IM/Nephrology

Kidney (Renal) Failure

Principal research interest is in the biology of chronic renal disease. Has made important contributions to the understanding of adaptations of ion transport in the diseased nephron, renal hypertrophy, and the cell biology of fibrogenesis and scarring of the kidney. Interest has focussed upon chronic hypoxia as driving force for organ fibrosis and possibility of diseased organ regeneration via restoration of microvasculature. Contributions to the history of medicine and renal diseases

  • Medical School: University of Cape Town, South Africa, 1966
  • Residency: Tel Aviv University, 1968
  • Residency: Tel Aviv University, 1970
  • Academy of Medical Sciences, UK, 1999
  • American Society for Clinical Investigation, 1982
  • Association of American Physicians, 1998
  • Director (non-excutive), National Insitute of Clinical Excellence, 2002
  • Editor-in-Chief: Experimental Nehrology, 1993 - 2002
  • Editor-in-Chief: Nephron Journals, 2004-2014
  • Founding Fellow, Academy of Medical Sciences, UK, 1999
  • President, Association of Physicians of Great Britain and Ireland, 1993

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  • Fine LG, Orphanides C, Norman JT: Progressive renal disease: the chronic hypoxia hypothesis. Kidney Int. Suppl., 65: S74-8, 1998
  • Kitamura M, Taylor S, Unwin R, Burton S, Shimizu F, Fine LG: Gene transfer into the rat renal glomerulus via a mesangial cell vector: site-specific delivery, in situ amplification, and sustained expression of an exogenous gene in vivo. J. Clin. Invest., 94(2): 497-505, 1994
  • Long DA, Norman JT, Fine LG: Restoring the renal microvasculature to treat chronic kidney disease. Nat Rev Nephrol, 8(4): 244-50, 2012
  • Norman JT, Fine LG: Intrarenal oxygenation in chronic renal failure. Clin. Exp. Pharmacol. Physiol., 33(10): 989-96, 2006
  • Fine LG. Ernest Henry Starling (1866-1927) on the formation and reabsorption of lymph. Nephron Physiol: 126:9-17, 2014

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English

Many of the physicians who have medical staff privileges to practice medicine at Cedars-Sinai Medical Center are independent physicians, and not employees or agents of the hospital. These independent physicians bill separately for their services. You should contact your physician to determine their status and billing practices.

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