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Shlomo Melmed, MD, ChB, FRCP, MACP, MB

Executive Vice President, Academic Affairs

Dean of the Medical Faculty

Helene A. and Philip E. Hixon Distinguished Chair in Investigative Medicine

Professor, Medicine

Cedars-Sinai Pituitary Center
127 S. San Vicente Blvd.
Advanced Health Sciences Pavilion, #A6600
Los Angeles, CA 90048

Phone:

310-423-2830

Fax:

310-423-2819

Parking Instructions:

Parking is available in Lot 4 by Advanced Health Sciences Pavilion (AHSP).

Cedars-Sinai Academic Affairs Administrative Office
8700 Beverly Blvd.
Room 2015
Los Angeles, CA 90048

Phone:

310-423-4691

Fax:

310-423-0119

Shlomo Melmed, MD, ChB, FRCP, MACP, MB

Executive Vice President, Academic Affairs

Dean of the Medical Faculty

Helene A. and Philip E. Hixon Distinguished Chair in Investigative Medicine

Professor, Medicine

  • IM/Endocrinology

Acromegaly

Pituitary Disorders

Pituitary Tumors

The research focus of Dr. Shlomo Melmed is molecular pathogenesis of pituitary tumors and pituitary receptor signaling. He employs molecular, cellular, transgenic animal and human tissue models to understand the biology of these commonly encountered hormone-secreting adenomas. He tests pituitary receptor signaling to develop novel peptide analog treatments for these tumors secreting growth hormone, prolactin, ACTH or gonadotropins.

  • Medical School: University of Capetown, 1970

View CV as a PDF

  • Editor-in-Chief: Pituitary, Current
  • Editor: DeGroot and Jameson Endocrinology, Current
  • Editor: Williams Textbook of Endocrinology, Current
  • Endocrine Regulation Prize, Fondation IPSEN, 2010
  • Transatlantic Medal, Society of Endocrinology, 2010
  • President, International Society of Endocrinology, 2004-08
  • Endocrine Society Clinical Investigator Award, 2004
  • President, Pituitary Society, 2002
  • Royal Society of Medicine, Clinical Endocrinology Trust Medal, 1994

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  • Chesnokova V, Zonis, Zhou C, Recouvreux V, Ben Shlomo A, Araki T, Barrett R, Workman M,Wawrowky K, Ljubimov VA, Uhart M, Melmed S: Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci USA 113(23):E3250-9, 2016.
  • Melmed S. Medical progress: Acromegaly. N Engl J Med. 2006;355(24):2558-2573.
  • Melmed S. Pathogenesis of pituitary tumors. Nat Rev Endocrinol. 2011;7(5):257-266.
  • Liu NA, Jiang H, Ben-Shlomo A, Wawrowsky K, Fan XM, Lin S, Melmed S. Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor. Proc Natl Acad Sci USA. 2011;108(20):8414-8419.
  • Fukuoka H, Cooper O, Ben-Shlomo A, Mamelak A, Ren SG, Bruyette D, Melmed S. EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas. J Clin Invest. 2011;121(12):4712-4721.
  • Zhou C, Jiao Y, Wang R, Ren SG, Wawrowsky K, Melmed S. STAT3 upregulation in pituitary somatotroph adenomas induces growth hormone hypersecretion. J Clin Invest. 2015 Apr;125(4):1692-1702.

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