Tyler M. Pierson, MD

Assistant Professor, Medicine

Assistant Professor, Pediatrics

Cedars-Sinai Medical Center
8700 Beverly Blvd.
North Tower, Suite 4221
Los Angeles, CA 90048





Parking Instructions:

Parking is available in front of Steven Spielberg Building in Lot 2.

Tyler M. Pierson, MD

Assistant Professor, Medicine

Assistant Professor, Pediatrics

  • Peds/Neurology
  • Pediatric Neurology & Neurosurgery


Cerebral Palsy

Muscular Dystrophy



Seizure Disorders (Epilepsy)


Stroke (Cerebrovascular Accident) - CVA

  • Residency: Texas Children's Hospital, 2002
  • Residency: Hospital of the University of Pennsylvania, 2003
  • Fellowship: The Children's Hospital of Philadelphia, 2007
  • Post Doctorate: National Institutes of Health, 2012

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  • American Neurological Association, 2014
  • Fashion Industries Guild Endowed Fellowship in Pediatric Neuromuscular Diseases, 2012
  • National Human Genome Research Institute Merit Award, 2011
  • Team Science Award, Society for Clinical and Translational Science, 2011
  • American Academy of Neurology, 2008
  • American Society of Gene and Cell Therapy, 2008
  • Child Neurology Society, 2006

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  • Pierson TM, Markello T, Accardi J, Wolfe L, Adams D, Sincan M, Tarazi NM, Fajardo KF, Cherukuri PF, Bajraktari I, et al. Novel SNP array analysis and exome sequencing detect a homozygous exon 7 deletion of MEGF10 causing early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD). Neuromuscul Disord. 2013;23(6):483-488.
  • Renvoisé B, Chang J, Singh R, Yonekawa S, FitzGibbon EJ, Mankodi A, Vanderver A, Schindler A, Toro C, Gahl WA, Mahuran DJ, Blackstone C, Pierson TM. Lysosomal abnormalities in hereditary spastic paraplegia types SPG15 and SPG11. Ann Clin Transl Neurol. 2014;1(6):379-389.
  • Yuan H, Hansen KB, Zhang J, Pierson TM, Markello TC, Fajardo KV, Holloman CM, Golas G, Adams DR, Boerkoel CF, et al. Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy. Nat Commun, 2014;5:3251.
  • Pierson TM, Yuan H, Marsh ED, Fuentes-Fajardo K, Adams DR, Markello T, Golas G, Simeonov DR, Holloman C, Tankovic A, et al. GRIN2A mutation and early-onset epileptic encephalopathy: personalized therapy with memantine. Ann Clin Transl Neurol. 2014;1(3):190-198.
  • Pizzino A, Pierson TM, Guo Y, Helman G, Fortini S, Guerrero K, Saitta S, Murphy JL, Padiath Q, Xie Y, et al. TUBB4A de novo mutations cause isolated hypomyelination. Neurology. 2014;83(10):898-902.
  • Zhu PP, Denton KR, Pierson TM, Li XJ, Blackstone C. Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A. Hum Mol Genet. 2014;23(21):5638-5648.

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