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Pramod Butte, PhD

Assistant Professor, Neurosurgery

Research Scientist, Maxine Dunitz Neurosurgical Institute

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Pramod Butte, PhD

Assistant Professor, Neurosurgery

Research Scientist, Maxine Dunitz Neurosurgical Institute

The research of Pramod Butte, PhD, focuses on translational research in the field of biophotoncs. Butte's lab is developing novel intra-operative imaging/visualization technologies to aid the surgeon in achieving near-complete tumor excision. He has also been exploring the technique of time-resolved laser induced fluorescence spectroscopy for delineation of primary brain tumors in near real-time. Butte is developing a novel near-infrared imaging system for visualizing a tumor marker which is used to tag the tumor and make them glow during surgery.

  • Medical School: Rural Medical College, 2000
  • Master's: University of Southern California, 2004
  • Doctorate: University of Southern California, 2006

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  • Society of Optical engineering, 2003-10
  • Society of Neuro-Oncology, 2009
  • Biomedical Engineering Society, 2005-07
  • American Society for Lasers in Medicine and Surgery, 2004-05

Click here for a list of peer-reviewed publications.

  • Butte PV, Fang Q, Jo JA, Yong WH, Pikul BK, Black KL, Marcu L. Intraoperative delineation of primary brain tumors using time-resolved fluorescence spectroscopy. J Biomed Opt. 2008;15(2):027008.
  • Butte PV, Mamelak A, Parrish-Novak J, Drazin D, Shweikeh F, Gangalum PR, Chesnokova A, Ljubimova JY, Black K. Near-infrared imaging of brain tumors using the Tumor Paint BLZ-100 to achieve near-complete resection of brain tumors. Neurosurg Focus. 2014;36(2):E1.
  • Butte PV, Mamelak AN, Nuno M, Bannykh SI, Black KL, Marcu L. Fluorescence lifetime spectroscopy for guided therapy of brain tumors. Neuroimage. 2011;54 Suppl 1:S125-135.
  • Butte PV, Pikul BK, Hever A, Yong WH, Black KL, Marcu L. Diagnosis of meningioma by time-resolved fluorescence spectroscopy. J Biomed Opt. 2005;10(6):064026.
  • Marcu L, Jo JA, Butte PV, Yong WH, Pikul BK, Black KL, Thompson RC. Fluorescence lifetime spectroscopy of glioblastoma multiforme. Photochem Photobiol. 2004;80:98-103.
  • Yong WH, Butte PV, Pikul BK, Jo JA, Fang Q, Papaioannou T, Black K, Marcu L. Distinction of brain tissue, low grade and high grade glioma with time-resolved fluorescence spectroscopy. Front. Biosci. 2006;11:1255-1263.
  • Lapchak PA, Boitano PD, Butte PV, Fisher DJ, Hölscher T, Ley EJ, Nuño M, Voie AH, Rajput PS. Transcranial near-infrared laser transmission (NILT) profiles (800 nm): systematic comparison in four common research species. PLoS One. 2015;10(6):e0127580.

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