FOR PREVIEW ONLY (Print)

William Parks, PhD

Scientific Director, Women's Guild Lung Institute

Associate Dean, Graduate Research Education

Director, Graduate Program in Biomedical and Translational Sciences

Professor, Medicine

Send an Email

Research Office:

Phone:

424-315-4307

William Parks, PhD

Scientific Director, Women's Guild Lung Institute

Associate Dean, Graduate Research Education

Director, Graduate Program in Biomedical and Translational Sciences

Professor, Medicine

The research of William Parks, PhD, focuses on the role of matrix metalloproteinases (MMPs) in immunity, tissue repair and fibrosis. With an emphasis on models of lung and skin diseases, his lab has determined that individual MMPs control distinct, non-overlapping functions in antimicrobial defense, epithelial repair and differentiation, leukocyte influx and activation, and resolution of fibrosis.

View NIH Biographical Sketch as a PDF

  • Doctorate: Medical College of Wisconsin, 1982
  • Post Doctorate: Michigan State University, 1984
  • Post Doctorate: Washington University School of Medicine, 1985
  • Associate Editor:Matrix Biology, Current
  • Consulting Editorial Board: Journal of Clinical Investigation, Current
  • Associate Editor: American Journal of Pathology, 2015-18
  • Deputy Editor: American Journal of Respiratory Cell and Molecular Biology, 2015-16
  • Scientific Achievement Award, American Thoracic Society, 2015
  • Founding Editor: Metalloproteinases in Medicine, 2013-15
  • Founding Editor: Journal of Inflammation Research, 2009-13
  • Endowed Chair in Pulmonary Disease Research, University of Washington, 2011
  • Lester I. Conrad Foundation Research Award in Dermatology, 1997
  • Genentech Scholar/American Lung Association Career Investigator Award, 1993

Show moreShow less

  • Rohani MG, Dimitrova E, Beppu A, Wang Y, Jefferies CA, Parks WC. Macrophage MMP10 Regulates TLR7-Mediated Tolerance. Front Immunol. 2018;9:2817.
  • Smigiel KS, Parks WC. Macrophages, Wound Healing, and Fibrosis: Recent Insights. Curr Rheumatol Rep. 2018;20(4):17.
  • McMahan RS, Birkland TP, Smigiel KS, Vandivort TC, Rohani MG, Manicone AM, McGuire JK, Gharib S, Parks WC. Stromelysin-2 (MMP10) moderates inflammation by controlling macrophage activation. J Immunol. 2016;197(3):899-909.
  • Secor PR, Michaels LA, Smigiel KS, Rohani MG, Jennings LK, Hisert KA, Arrigoni A, Braun KR, Birkland TP, Lai Y, Hallstrand TS, Bollyky PL, Singh PK, Parks WC. 2016. Filamentous bacteriophage produced by Pseudomonas aeruginosa alters the inflammatory response and promotes non-invasive infection in vivo. Infect Immun 85:e00648-16.
  • Secor PR, Sweere J, Michaels LA, Malkovskiy AV, Lazzareschi D, Katznelson E, Arrigoni A, Braun KR, Evanko SP, Kaminsky W, Singh PK, Parks WC*, et al. Filamentous bacteriophage promote biofilm assembly and function. Cell Host Microbe. 2015;18(5):549-559. *Co-senior authors
  • Parks WC, Wilson CL, Lopez-Boado YS. Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol. 2004;4(8):617-629.
  • Li Q, Park PW, Wilson CL, Parks WC. Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury. Cell. 2002;111(5):635-646.

Show moreShow less

Many of the physicians who have medical staff privileges to practice medicine at Cedars-Sinai Medical Center are independent physicians, and not employees or agents of the hospital. These independent physicians bill separately for their services. You should contact your physician to determine their status and billing practices.

Send Email to William Parks, PhD