Keith L. Black, MD

Chair, Department of Neurosurgery

Ruth and Lawrence Harvey Chair in Neuroscience

Director, Maxine Dunitz Neurosurgical Institute

Professor, Neurosurgery

Advanced Health Sciences Pavilion, A6600
127 S. San Vicente Blvd.
Los Angeles, CA 90048





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Keith L. Black, MD

Chair, Department of Neurosurgery

Ruth and Lawrence Harvey Chair in Neuroscience

Director, Maxine Dunitz Neurosurgical Institute

Professor, Neurosurgery

  • Neurosurgery
  • Brain Tumor

Acoustic Neuromas


Brain Cancers (Glioma)

Brain Stem Glioma

Brain Tumors

Cavernous Angioma

Cerebellopontine Angle Syndrome

Colloid Cysts


Glioblastoma Multiforme


Intraventricular Tumors





Orbital Tumors

Pineal Tumors

Pituitary Tumors


Skull Base Tumors

Spine Tumors (Cervical, Thoracic, Lumbar, Sacral)

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The research of Keith L Black, MD, focuses on biology of blood-brain barrier (BBB) and biochemical modulation of the blood-brain tumor barrier (BTB), targeted drug delivery, tumor immunology, cancer vaccines, cancer stem cells, microwave tumor ablation, nanotechnology for drug delivery, optical guided surgery for brain tumors, and Alzheimer's retinal imaging.

View NIH Biographical Sketch as a PDF

  • Medical School: University of Michigan School of Medicine, 1981
  • Internship: University of Michigan School of Medicine, 1982
  • Residency: University of Michigan School of Medicine, 1987

View CV as a PDF

  • Editorial Board: Public Library of Science (PLoS), Current
  • America's Top Doctors and Best Doctors in America, 2007, Current
  • Cedars-Sinai Pioneer in Medicine Award, 2018
  • Whitney M. Young, Jr. Living Legend Award, National Urban League, 2011
  • Special Recognition, National Academy of Science, 2000
  • Jacobs Javitz Award, NIH National Institute of Neurological Disorders and Stroke, 2000
  • Golden Plate Award, American Academy of Achievement, 1999
  • Cover of Time Magazine, "Heroes of Medicine", 1997
  • American Academy of Neurological Surgery, 1995
  • Neurosurgical Society of America, 1993
  • American Association of Neurological Surgeons, 1991
  • Congress of Neurological Surgeons, 1982

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Click here for a list of peer-reviewed publications.

  • Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee W, Furnari F, Ljubimov V, Shatalova E, Wagner S, Li D, Mamelak AN, Bannykh S, Patil CG, Rudnick J, Hu J, Grodzinski Z, Rekechenetskiy A, Falahatian V, Lyubimov A, Leoh LS, Chen YM, Daniels-Wells T, Penichet P, Holler E, Ljubimov A, Black KL, Ljubimova JY. Blockade of a laminin-411 - Notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment crosstalk. Cancer Res 2019 Jan 18. pii: canres.2725.2018. doi: 10.1158/0008-5472.CAN-18-2725.
  • Kittle D, Vasefi F, Patil CG, Mamelak AN, Black KL, Butte PV. Real time optical Biopsy: Time-resolved Fluorescence Spectroscopy instrumentation and validation. Scientific Reports. 2016 Dec 8;6:38190. doi: 10.1038/srep38190
  • Chou S, Gangalum PR, Patil P, Cavenee WK, Furnari F, Galstyan A, DingH, Chesnokova A, Mashouf A, Fox I, Black KL, Holler E, Ljubimov AV, Ljubimova. JY. Simultaneous blockade of CK2 and EGFR pathways by tumor-targeted nanobioconjugates significantly improves therapeutic efficacy against glioblastoma multiforme. J Control Release. 244 (2016) 14-23. doi: 10.1016/j.jconrel.2016.11.001.
  • Butte PV, Mamelak AN, Parrish-Novak J, Drazin D, Shweikeh F, Gangalum PR, Chesnokova A, Ljubimova JY, Black KL. Near-infrared imaging of brain tumors using the Tumor PaintTM BLZ-100 to achieve near-complete resection of brain tumors. Neurosurg Focus. 2014;36(2):E1.
  • Jeswani S, Nuno M, Folkerts V, Mukherjee D, Black KL, Patil CG. Comparison of survival between cerebellar and supratentorial glioblastoma patients: surveillance, epidemiology, and end results (SEER) analysis. Neurosurgery. 2013;73(2):240-246.
  • Phuphanich S, Wheeler CJ, Rudnick JD, Mazer M, Wang H, Nuno MA, Richardson JE, Fan X, Ji J, Chu RM, Bender JG, Hawkins ES, Patil CG, Black KL, et al. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma. Cancer Immunol Immunother. 2013;62(1):125-135.
  • Wheeler CJ, Black KL. Vaccines for glioblastoma and high-grade glioma. Expert Rev Vaccines. 2011;10(6):875-886.

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